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FBXO11 抗体

FBXO11 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7261998
发货至: 中国
  • 抗原 See all FBXO11 抗体
    FBXO11 (F-Box Protein 11 (FBXO11))
    适用
    • 62
    • 18
    • 16
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 56
    • 5
    • 1
    克隆类型
    • 59
    • 3
    多克隆
    标记
    • 27
    • 5
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    • 2
    • 2
    • 1
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    • 1
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    This FBXO11 antibody is un-conjugated
    应用范围
    • 33
    • 25
    • 13
    • 13
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human FBXO11 (NP_001177203.1).
    亚型
    IgG
    Top Product
    Discover our top product FBXO11 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF 1:20-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FBXO11 (F-Box Protein 11 (FBXO11))
    别名
    FBXO11 (FBXO11 产品)
    别名
    FBX11 antibody, PRMT9 antibody, UBR6 antibody, VIT1 antibody, C80048 antibody, Jf antibody, Vit1 antibody, fbxo11 antibody, MGC84634 antibody, FBXO11 antibody, im:6906507 antibody, wu:fj83f06 antibody, zgc:153171 antibody, Fbxo11 antibody, DKFZp459P2410 antibody, F-box protein 11 antibody, F-box protein 11 L homeolog antibody, F-box protein 11a antibody, F-box only protein 11 antibody, hypothetical protein antibody, FBXO11 antibody, Fbxo11 antibody, fbxo11.L antibody, fbxo11a antibody, CpipJ_CPIJ009919 antibody, CpipJ_CPIJ017549 antibody, Bm1_52225 antibody, LOAG_16571 antibody, fbxo11 antibody, LOC100115478 antibody
    背景
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
    分子量

    Observed_MW: 130 kDa

    Calculated_MW: 23 kDa/62 kDa/65 kDa/94 kDa/103 kDa/106 kDa

    基因ID
    80204
    UniProt
    Q86XK2
    途径
    Sensory Perception of Sound
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