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- 抗原 See all FBXO11 抗体
- FBXO11 (F-Box Protein 11 (FBXO11))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXO11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human FBXO11 (NP_001177203.1).
- 亚型
- IgG
- Top Product
- Discover our top product FBXO11 Primary Antibody
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anti-F-Box Protein 11 (FBXO11) (AA 744-843) antibody
FBXO11 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 65-160) antibodyFBXO11 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 1-843) antibodyFBXO11 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 744-844) antibodyFBXO11 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-F-Box Protein 11 (FBXO11) (Middle Region) antibodyFBXO11 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 犬, 豚鼠, 兔 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (Internal Region) antibodyFBXO11 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 181-453) antibodyFBXO11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 754-765) antibodyVerified FBXO11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (C-Term) antibodyFBXO11 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 犬, 豚鼠, 兔, 非洲爪蟾, 小鸡, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 726-775) antibodyFBXO11 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 犬, 豚鼠, 兔, 非洲爪蟾, 小鸡, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IF 1:20-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FBXO11 (F-Box Protein 11 (FBXO11))
- 别名
- FBXO11 (FBXO11 产品)
- 背景
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
- 分子量
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Observed_MW: 130 kDa
Calculated_MW: 23 kDa/62 kDa/65 kDa/94 kDa/103 kDa/106 kDa
- 基因ID
- 80204
- UniProt
- Q86XK2
- 途径
- Sensory Perception of Sound
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