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NPRL2 抗体

NPRL2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7261820
发货至: 中国
  • 抗原 See all NPRL2 抗体
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    适用
    • 53
    • 31
    • 18
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 2
    • 1
    克隆类型
    • 53
    多克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPRL2 antibody is un-conjugated
    应用范围
    • 45
    • 22
    • 13
    • 13
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human NPRL2 (NP_006536.3).
    亚型
    IgG
    Top Product
    Discover our top product NPRL2 Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    别名
    NPRL2 (NPRL2 产品)
    别名
    2810446G01Rik antibody, G21 antibody, NPR2L antibody, Tusc4 antibody, npr2 antibody, npr2l antibody, tusc4 antibody, NPR2 antibody, TUSC4 antibody, im:6900399 antibody, zgc:153630 antibody, nitrogen permease regulator-like 2 antibody, NPR2 like, GATOR1 complex subunit S homeolog antibody, NPR2 like, GATOR1 complex subunit antibody, NPR2-like, GATOR1 complex subunit antibody, Nprl2 antibody, nprl2.S antibody, NPRL2 antibody, nprl2 antibody
    背景
    NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain. It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart. NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression. NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways. It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment. The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.
    基因ID
    10641
    UniProt
    Q8WTW4
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