PPARD 抗体
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- 抗原 See all PPARD 抗体
- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPARD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human PPARD (NP_803184.1).
- 亚型
- IgG
- Top Product
- Discover our top product PPARD Primary Antibody
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- 应用备注
- WB 1:500-1:2000 IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
- 别名
- PPARD (PPARD 产品)
- 别名
- FAAR antibody, NR1C2 antibody, NUC1 antibody, NUCI antibody, NUCII antibody, PPARB antibody, NUC-1 antibody, Nr1c2 antibody, PPAR-beta antibody, PPAR-delta antibody, PPAR[b] antibody, PPARdelta antibody, Pparb antibody, Pparb/d antibody, PPARBETA antibody, ppard antibody, pparb antibody, PPARD antibody, PPAR-D/B antibody, peroxisome proliferator activated receptor delta antibody, peroxisome proliferator activator receptor delta antibody, peroxisome proliferator activated receptor delta S homeolog antibody, peroxisome proliferator-activated receptor delta antibody, PPARD antibody, Ppard antibody, ppard.S antibody, ppard antibody
- 背景
- This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 56 kDa
Calculated_MW: 38 kDa/40 kDa/45 kDa/49 kDa
- 基因ID
- 5467
- UniProt
- Q03181
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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