APLP2 抗体
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- 抗原 See all APLP2 抗体
- APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APLP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human APLP2 (NP_001135750.1).
- 亚型
- IgG
- Top Product
- Discover our top product APLP2 Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
- 别名
- APLP2 (APLP2 产品)
- 背景
- This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- 分子量
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Observed_MW: 87 kDa
Calculated_MW: 59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa
- 基因ID
- 334
- UniProt
- Q06481
- 途径
- EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour
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