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GTF2H2 抗体

GTF2H2 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7261267
发货至: 中国
  • 抗原 See all GTF2H2 抗体
    GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
    适用
    • 38
    • 18
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 32
    • 6
    克隆类型
    • 33
    • 5
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GTF2H2 antibody is un-conjugated
    应用范围
    • 19
    • 12
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human GTF2H2 (NP_001506.1).
    亚型
    IgG
    Top Product
    Discover our top product GTF2H2 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
    别名
    GTF2H2 (GTF2H2 产品)
    别名
    44kDa antibody, BTF2 p44 antibody, BTF2-p44 antibody, Btf2p44 antibody, p44 antibody, BTF2 antibody, BTF2P44 antibody, T-BTF2P44 antibody, TFIIH antibody, general transcription factor II H, polypeptide 2 antibody, general transcription factor IIH subunit 2 antibody, general transcription factor IIH, polypeptide 2, 44kDa antibody, Gtf2h2 antibody, GTF2H2 antibody
    背景
    This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.
    基因ID
    2966
    UniProt
    Q13888
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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