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- 抗原 See all ROBO3 抗体
- ROBO3 (Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ROBO3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human ROBO3 (NP_071765.2).
- 亚型
- IgG
- Top Product
- Discover our top product ROBO3 Primary Antibody
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anti-Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3) (AA 1-147) antibody
ROBO3 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3) (Internal Region) antibodyVerified ROBO3 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3) (AA 1237-1386) antibodyROBO3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3) (AA 1-147) antibodyROBO3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3) (Internal Region) antibodyVerified ROBO3 适用: 人 ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3) (AA 1-147) antibodyROBO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ROBO3 (Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
- 别名
- ROBO3 (ROBO3 产品)
- 别名
- HGPPS antibody, HGPS antibody, RBIG1 antibody, RIG1 antibody, CG14345 antibody, CT17158 antibody, Robo-3 antibody, Robo3 antibody, dRobo-3 antibody, DmelCG5423 antibody, CG5423 antibody, ROBO3 antibody, robo3 antibody, DKFZp468G0223 antibody, Rbig1 antibody, Rig-1 antibody, Rig1 antibody, Robo3a antibody, Robo3b antibody, cb503 antibody, roundabout guidance receptor 3 antibody, roundabout 3 antibody, robo3 antibody, roundabout guidance receptor 3 L homeolog antibody, roundabout, axon guidance receptor, homolog 3 (Drosophila) antibody, ROBO3 antibody, robo3 antibody, Robo3 antibody, LOC658818 antibody, robo3.L antibody
- 背景
- This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS), an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated.
- 分子量
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Observed_MW: 200 kDa
Calculated_MW: 110 kDa/148 kDa
- 基因ID
- 64221
- UniProt
- Q96MS0
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