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ALS2 抗体

ALS2 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7010503
发货至: 中国
  • 抗原 See all ALS2 抗体
    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
    适用
    • 43
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 3
    • 1
    克隆类型
    • 41
    • 2
    多克隆
    标记
    • 24
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALS2 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human ALS2 (NP_065970.2).
    亚型
    IgG
    Top Product
    Discover our top product ALS2 Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
    别名
    ALS2 (ALS2 产品)
    背景
    The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
    基因ID
    57679
    UniProt
    Q96Q42
    途径
    Skeletal Muscle Fiber Development
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