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Bestrophin 1 抗体

BEST1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7260777
发货至: 中国
  • 抗原 See all Bestrophin 1 (BEST1) 抗体
    Bestrophin 1 (BEST1)
    适用
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 21
    • 4
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bestrophin 1 antibody is un-conjugated
    应用范围
    • 16
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human BEST1 (NP_004174.1).
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Bestrophin 1 (BEST1)
    别名
    BEST1 (BEST1 产品)
    别名
    CG6264 antibody, Dbest antibody, Dmel\\CG6264 antibody, anon-WO0118547.380 antibody, best antibody, dBest1 antibody, dbest1 antibody, dmBest1 antibody, BEST1 antibody, VMD2 antibody, best-1 antibody, ARB antibody, BEST antibody, BMD antibody, RP50 antibody, TU15B antibody, Bmd antibody, Vmd2 antibody, mBest1 antibody, Bestrophin 1 antibody, bestrophin 1 antibody, Best1 antibody, BEST1 antibody, best1 antibody, Bm1_25500 antibody
    背景
    This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
    分子量

    Observed_MW: 70 kDa

    Calculated_MW: 57 kDa/67 kDa/69 kDa

    基因ID
    7439
    UniProt
    O76090
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