PGC 抗体
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- 抗原 See all PGC 抗体
- PGC (Pepsinogen C (PGC))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PGC antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human Pepsinogen II (NP_001159896.1).
- 亚型
- IgG
- Top Product
- Discover our top product PGC Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PGC (Pepsinogen C (PGC))
- 别名
- Pepsinogen II (PGC 产品)
- 别名
- PEPC antibody, PGII antibody, 2210410L06Rik antibody, Upg-1 antibody, Upg1 antibody, CPGC antibody, gastricsin antibody, PG1 antibody, Pg-1 antibody, PGNC antibody, PGC antibody, Gastricsin antibody, progastricsin (pepsinogen C) antibody, progastricsin antibody, PGC antibody, Pgc antibody
- 背景
- This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
- 分子量
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Observed_MW: 45-50 kDa
Calculated_MW: 34 kDa/42 kDa
- 基因ID
- 5225
- UniProt
- P20142
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