ADAM10 抗体 (AA 501-600) (Biotin)
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- 抗原 See all ADAM10 抗体
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
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抗原表位
- AA 501-600
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAM10 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ADAM10
- 亚型
- IgG
- Top Product
- Discover our top product ADAM10 Primary Antibody
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anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 420-641) antibody
ADAM10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibodyADAM10 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6C3C7 unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 400-414), (Extracellular), (N-Term) antibodyADAM10 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 501-600) antibodyADAM10 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibodyADAM10 适用: 人 WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 11G2 unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 732-748) antibodyADAM10 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody (PE)ADAM10 适用: 人 FACS 宿主: 小鼠 Monoclonal 11G2 PE
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 214-500) antibodyADAM10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibodyADAM10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 218-445) antibodyADAM10 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
- 别名
- ADAM10 (ADAM10 产品)
- 别名
- ADAM10 antibody, Adam10 antibody, adam10 antibody, wu:fc03d12 antibody, ad10 antibody, cd156c antibody, kuz antibody, kuzbanian antibody, madm antibody, xadam10 antibody, ADAM-10 antibody, ADAM 10 antibody, AD10 antibody, CD156c antibody, HsT18717 antibody, MADM antibody, 1700031C13Rik antibody, LOC100219653 antibody, zgc:64203 antibody, ADAM metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10a antibody, ADAM metallopeptidase domain 10 S homeolog antibody, a disintegrin and metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10b antibody, ADAM10 antibody, Adam10 antibody, adam10a antibody, adam10.S antibody, adam10b antibody
- 背景
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Synonyms: RAK, kuz, AD10, AD18, MADM, CD156c, HsT18717, Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease, ADAM10
Background: Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis. Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form. Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B. May regulate the EFNA5-EPHA3 signaling.
- 基因ID
- 102
- UniProt
- O14672
- 途径
- Notch Signaling, EGFR Signaling Pathway
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