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ADAM10 抗体 (AA 501-600)

Name: ADAM10 抗体 (AA 501-600)
SKU: ABIN701020
Availability: OutOfStock

ADAM10 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ADAM10 Polyclonal Antibody, Unconjugated (ABIN701020) at 1:200 followed by conjugation to the secondary antibody and DAB staining (ADAM10 抗体 (AA 501-600))

IHC

1 image

(3 references)

产品编号 ABIN701020

发货至: 中国

Datasheet as PDF

抗原 See all ADAM10 抗体

ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
抗原表位
14

5

5

4

3

2

2

1

1

1

1

1

1

1

1

1
AA 501-600
适用
65

28

28

1

1

1
人, 大鼠, 小鼠
宿主
54

11

2

1
兔
Compatible Secondaries
克隆类型
48

20
多克隆
标记
30

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This ADAM10 antibody is un-conjugated
应用范围
42

14

14

14

12

12

7

6

6

5

3

3

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human ADAM10

亚型

IgG

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anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 420-641) antibody
ADAM10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody
ADAM10 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6C3C7 unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 400-414), (Extracellular), (N-Term) antibody
ADAM10 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody
ADAM10 适用: 人 WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 11G2 unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 732-748) antibody
ADAM10 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody (PE)
ADAM10 适用: 人 FACS 宿主: 小鼠 Monoclonal 11G2 PE

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 214-500) antibody
ADAM10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody
ADAM10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 218-445) antibody
ADAM10 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (C-Term) antibody
ADAM10 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

Angenendt, Reuter, Kentrup, Benk, Neumann, Hüve, Martens, Schwöppe, Kessler, Schmidt, Sauer, Brand, Mikesch, Lenz, Mesters, Müller-Tidow, Hartmann, Wardelmann, Neri, Berdel, Roesli, Schliemann: "An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia." in: Leukemia, Vol. 32, Issue 2, pp. 510-519, (2017) (PubMed).

Li, Xie, He, Wang, Duan, Yang, Wang: "Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis." in: Gene, Vol. 562, Issue 1, pp. 117-27, (2015) (PubMed).
抗原

ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

别名

ADAM10 (ADAM10 产品)

别名

ADAM10 antibody, Adam10 antibody, adam10 antibody, wu:fc03d12 antibody, ad10 antibody, cd156c antibody, kuz antibody, kuzbanian antibody, madm antibody, xadam10 antibody, ADAM-10 antibody, ADAM 10 antibody, AD10 antibody, CD156c antibody, HsT18717 antibody, MADM antibody, 1700031C13Rik antibody, LOC100219653 antibody, zgc:64203 antibody, ADAM metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10a antibody, ADAM metallopeptidase domain 10 S homeolog antibody, a disintegrin and metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10b antibody, ADAM10 antibody, Adam10 antibody, adam10a antibody, adam10.S antibody, adam10b antibody

背景

Synonyms: RAK, kuz, AD10, AD18, MADM, CD156c, HsT18717, Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease, ADAM10
Background: Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis. Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form. Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B. May regulate the EFNA5-EPHA3 signaling.

基因ID

102

UniProt

O14672

途径

Notch Signaling, EGFR Signaling Pathway