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PCBP2 抗体

PCBP2 适用: 人, 小鼠, 斑马鱼 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7260491
发货至: 中国
  • 抗原 See all PCBP2 抗体
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    适用
    • 35
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    • 6
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    • 4
    • 2
    • 2
    • 2
    • 1
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    人, 小鼠, 斑马鱼
    宿主
    • 32
    • 4
    克隆类型
    • 31
    • 5
    多克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
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    This PCBP2 antibody is un-conjugated
    应用范围
    • 24
    • 12
    • 12
    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human PCBP2 (NP_001122383.1).
    亚型
    IgG
    Top Product
    Discover our top product PCBP2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    别名
    PCBP2 (PCBP2 产品)
    别名
    HNRNPE2 antibody, HNRPE2 antibody, hnRNP-E2 antibody, AW412548 antibody, Hnrpx antibody, alphaCP-2 antibody, PCBP3 antibody, fb36h02 antibody, wu:fb36h02 antibody, zgc:55964 antibody, PCBP2 antibody, poly(rC) binding protein 2 antibody, poly(rC) binding protein 2 L homeolog antibody, PCBP2 antibody, Pcbp2 antibody, pcbp2 antibody, pcbp2.L antibody
    背景
    The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 39 kDa

    Calculated_MW: 33 kDa/34 kDa/35 kDa/38 kDa

    基因ID
    5094
    UniProt
    Q15366
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