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DNMT3L 抗体

TRDMT1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7260352
发货至: 中国
  • 抗原 See all DNMT3L (TRDMT1) 抗体
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    适用
    • 72
    • 16
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 71
    • 6
    克隆类型
    • 73
    • 4
    多克隆
    标记
    • 33
    • 7
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    • 6
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    • 4
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This DNMT3L antibody is un-conjugated
    应用范围
    • 65
    • 38
    • 15
    • 13
    • 13
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human DNMT3L (NP_787063.1).
    亚型
    IgG
    Top Product
    Discover our top product TRDMT1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200 IF 1:20-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    别名
    DNMT3L (TRDMT1 产品)
    别名
    DNMT3L antibody, D6Ertd14e antibody, ecat7 antibody, DNA methyltransferase 3 like antibody, DNA (cytosine-5-)-methyltransferase 3-like antibody, DNMT3L antibody, Dnmt3l antibody
    背景
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    基因ID
    29947
    UniProt
    Q9UJW3
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