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PITX2 抗体

PITX2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259893
发货至: 中国
  • 抗原 See all PITX2 抗体
    PITX2 (Paired-Like Homeodomain 2 (PITX2))
    适用
    • 48
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 42
    • 5
    • 1
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PITX2 antibody is un-conjugated
    应用范围
    • 36
    • 28
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human PITX2 (NP_000316.2).
    亚型
    IgG
    Top Product
    Discover our top product PITX2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PITX2 (Paired-Like Homeodomain 2 (PITX2))
    别名
    PITX2 (PITX2 产品)
    背景
    This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
    分子量

    Observed_MW: 39 kDa

    Calculated_MW: 30 kDa/35 kDa

    基因ID
    5308
    UniProt
    Q99697
    途径
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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