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- 抗原 See all POLH 抗体
- POLH (Polymerase (DNA Directed), eta (POLH))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLH antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human DNA polymerase eta (NP_006493.1).
- 亚型
- IgG
- Top Product
- Discover our top product POLH Primary Antibody
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anti-Polymerase (DNA Directed), eta (POLH) (AA 408-609) antibody
POLH 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 20-320) antibodyPOLH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 1-713) antibodyPOLH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 1-713) antibodyPOLH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (Internal Region) antibodyPOLH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 157-361) antibodyPOLH 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- POLH (Polymerase (DNA Directed), eta (POLH))
- 别名
- DNA polymerase eta (POLH 产品)
- 背景
- This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
- 分子量
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Observed_MW: 70 kDa
Calculated_MW: 46 kDa/78 kDa
- 基因ID
- 5429
- UniProt
- Q9Y253
- 途径
- DNA Damage Repair
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