BIN1 抗体
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- 抗原 See all BIN1 抗体
- BIN1 (Bridging Integrator 1 (BIN1))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human BIN1 (NP_647601.1).
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- BIN1 (Bridging Integrator 1 (BIN1))
- 别名
- BIN1 (BIN1 产品)
- 别名
- bin1 antibody, MGC53185 antibody, amph2 antibody, amphl antibody, sh3p9 antibody, MGC76187 antibody, cb57 antibody, zgc:86701 antibody, BIN1 antibody, AMPH2 antibody, AMPHL antibody, SH3P9 antibody, ALP-1 antibody, Amphl antibody, BRAMP-2 antibody, bridging integrator 1 antibody, bridging integrator 1 S homeolog antibody, bridging integrator 1b antibody, BIN1 antibody, bin1.S antibody, bin1 antibody, bin1b antibody, Bin1 antibody
- 背景
- This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
- 分子量
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Observed_MW: 65 kDa
Calculated_MW: 45-64 kDa
- 基因ID
- 274
- UniProt
- O00499
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