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BIN1 抗体

BIN1 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259755
发货至: 中国
  • 抗原 See all BIN1 抗体
    BIN1 (Bridging Integrator 1 (BIN1))
    适用
    • 44
    • 23
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 29
    • 15
    • 1
    克隆类型
    • 29
    • 16
    多克隆
    标记
    • 36
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIN1 antibody is un-conjugated
    应用范围
    • 33
    • 17
    • 15
    • 10
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human BIN1 (NP_647601.1).
    亚型
    IgG
    Top Product
    Discover our top product BIN1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    BIN1 (Bridging Integrator 1 (BIN1))
    别名
    BIN1 (BIN1 产品)
    背景
    This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
    分子量

    Observed_MW: 65 kDa

    Calculated_MW: 45-64 kDa

    基因ID
    274
    UniProt
    O00499
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