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AIRE 抗体

This anti-AIRE antibody is a 兔 多克隆 antibody detecting AIRE in IF. Suitable for 人 和 小鼠.
产品编号 ABIN7259713
发货至: 中国

Quick Overview for AIRE 抗体 (ABIN7259713)

抗原

See all AIRE 抗体
AIRE (Autoimmune Regulator (AIRE))

适用

  • 54
  • 25
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
人, 小鼠

宿主

  • 50
  • 7
  • 1
  • 1

克隆类型

  • 57
  • 1
多克隆

标记

  • 43
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AIRE antibody is un-conjugated

应用范围

  • 45
  • 27
  • 19
  • 14
  • 12
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide of human AIRE (NP_000374.1).

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    AIRE (Autoimmune Regulator (AIRE))

    别名

    AIRE

    背景

    This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

    基因ID

    326

    UniProt

    O43918

    途径

    Chromatin Binding
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