NAIP 抗体
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- 抗原 See all NAIP 抗体
- NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAIP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human NAIP (NP_075043.1).
- 亚型
- IgG
- Top Product
- Discover our top product NAIP Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
- 别名
- NAIP (NAIP 产品)
- 别名
- BIRC1 antibody, NLRB1 antibody, psiNAIP antibody, AV364616 antibody, Birc1a antibody, D13Lsd1 antibody, Naip antibody, Naip-rs1 antibody, NLR family apoptosis inhibitory protein antibody, NLR family, apoptosis inhibitory protein 1 antibody, NAIP antibody, Naip1 antibody
- 背景
- This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
- 分子量
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Observed_MW: 160 kDa
Calculated_MW: 159 kDa
- 基因ID
- 4671
- UniProt
- Q13075
- 途径
- Apoptosis, Inflammasome
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