IFI35 抗体
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- 抗原 See all IFI35 抗体
- IFI35 (Interferon-Induced Protein 35 (IFI35))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IFI35 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human IFI35 (NP_005524.2).
- 亚型
- IgG
- Top Product
- Discover our top product IFI35 Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- IFI35 (Interferon-Induced Protein 35 (IFI35))
- 别名
- IFI35 (IFI35 产品)
- 别名
- IFI35 antibody, IFP35 antibody, 2010008K16Rik antibody, AW986054 antibody, ifi-35 antibody, interferon induced protein 35 antibody, interferon-induced protein 35 antibody, IFI35 antibody, ifi35 antibody, Ifi35 antibody
- 背景
- The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.
- 分子量
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Observed_MW: 35 kDa
Calculated_MW: 31 kDa
- 基因ID
- 3430
- UniProt
- P80217
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