eml4 antibody, MGC89332 antibody, EML4 antibody, C2orf2 antibody, ELP120 antibody, EMAP-4 antibody, EMAPL4 antibody, ROPP120 antibody, 4930443C24Rik antibody, AI644019 antibody, echinoderm microtubule associated protein like 4 antibody, echinoderm microtubule associated protein like 4 S homeolog antibody, Eml4 antibody, EML4 antibody, eml4 antibody, eml4.S antibody
背景
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.