Laminin gamma 1 抗体
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- 抗原 See all Laminin gamma 1 (LAMC1) 抗体
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Laminin gamma 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human LAMC1 (NP_002284.3).
- 亚型
- IgG
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anti-Laminin, gamma 1 (LAMC1) (AA 1300-1609) antibody
LAMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (all Isoforms) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 521-772) antibodyLAMC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1333-1607) antibodyLAMC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6-B4 unconjugated
anti-Laminin, gamma 1 (LAMC1) (N-Term) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyLAMC1 适用: 小鼠 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1566-1579) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (C-Term) antibodyLAMC1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:50-1:200 IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
- 别名
- LAMC1 (LAMC1 产品)
- 别名
- lamb2 antibody, Lamb2 antibody, B2e antibody, sly antibody, LAMB2 antibody, putative laminin gamma-1 chain antibody, laminin subunit gamma 1 antibody, laminin, gamma 1 antibody, Smp_163810 antibody, lamc1 antibody, Lamc1 antibody, LAMC1 antibody
- 背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.
- 基因ID
- 3915
- UniProt
- P11047
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