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UNC13B 抗体

UNC13B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7258666
发货至: 中国
  • 抗原 See all UNC13B 抗体
    UNC13B (Unc-13 Homolog B (UNC13B))
    适用
    • 31
    • 17
    • 2
    人, 小鼠
    宿主
    • 40
    • 2
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC13B antibody is un-conjugated
    应用范围
    • 31
    • 26
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human UNC13B (NP_006368.3).
    亚型
    IgG
    Top Product
    Discover our top product UNC13B Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    UNC13B (Unc-13 Homolog B (UNC13B))
    别名
    UNC13B (UNC13B 产品)
    别名
    MUNC13 antibody, UNC13 antibody, Unc13h2 antibody, UNC13B antibody, Munc13-2 antibody, Munc13-1 antibody, Unc13a antibody, Unc13h1 antibody, unc-13 homolog B antibody, unc-13 homolog B (C. elegans) antibody, UNC13B antibody, Unc13b antibody
    背景
    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
    分子量

    Observed_MW: 210 kDa

    Calculated_MW: 180 kDa/182 kDa

    基因ID
    10497
    UniProt
    O14795
    途径
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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