PACAP antibody, pERp1 antibody, MEDA-7 antibody, Pacap antibody, RGD1310251 antibody, 2010001M09Rik antibody, AV064572 antibody, marginal zone B and B1 cell specific protein antibody, marginal zone B and B1 cell-specific protein antibody, marginal zone B and B1 cell-specific protein 1 antibody, MZB1 antibody, Mzb1 antibody
背景
Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.