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TPSAB1 抗体

TPSAB1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7257888
发货至: 中国
  • 抗原 See all TPSAB1 抗体
    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
    适用
    • 49
    • 30
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 63
    • 21
    • 2
    • 1
    克隆类型
    • 67
    • 20
    多克隆
    标记
    • 48
    • 16
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPSAB1 antibody is un-conjugated
    应用范围
    • 68
    • 38
    • 29
    • 13
    • 12
    • 11
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human TPSAB1 (NP_003285.2).
    亚型
    IgG
    Top Product
    Discover our top product TPSAB1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
    别名
    TPSAB1 (TPSAB1 产品)
    背景
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
    基因ID
    7177
    UniProt
    Q15661
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