CAND1 抗体
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- 抗原 See all CAND1 抗体
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAND1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human CAND1 (NP_060918.2).
- 亚型
- IgG
- Top Product
- Discover our top product CAND1 Primary Antibody
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- 应用备注
- IHC 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- 别名
- CAND1 (CAND1 产品)
- 背景
- This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.
- 基因ID
- 55832
- UniProt
- Q86VP6
- 途径
- Regulation of Actin Filament Polymerization
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