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IQGAP3 抗体

IQGAP3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7257710
发货至: 中国
  • 抗原 See all IQGAP3 products
    IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))
    适用
    • 26
    • 12
    • 4
    • 1
    人, 小鼠, 大鼠
    宿主
    • 21
    • 5
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IQGAP3 antibody is un-conjugated
    应用范围
    • 18
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human IQGAP3 (NP_839943.2).
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))
    别名
    IQGAP3 (IQGAP3 产品)
    别名
    IQGAP3 antibody, AI593484 antibody, D030034H08 antibody, IQ motif containing GTPase activating protein 3 antibody, IQGAP3 antibody, iqgap3 antibody, Iqgap3 antibody
    背景
    IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
    分子量

    Observed_MW: 170 kDa

    Calculated_MW: 184 kDa

    基因ID
    128239
    UniProt
    Q86VI3
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