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TPMT 抗体
TPMT
适用: 人, 小鼠
IF
宿主: 兔
Polyclonal
unconjugated
TPMT抗体详情
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抗原
See all TPMT 抗体
TPMT
(Thiopurine S-Methyltransferase (TPMT))
适用
All reactivities for TPMT 抗体
人, 小鼠
宿主
All hosts for TPMT 抗体
兔
克隆类型
All clonalities for TPMT 抗体
多克隆
标记
All conjugates for TPMT 抗体
This TPMT antibody is un-conjugated
应用范围
All applications for TPMT 抗体
Immunofluorescence (IF)
产品特性
Polyclonal Antibody
纯化方法
Affinity purification
免疫原
Recombinant fusion protein of human TPMT (NP_000358.1).
亚型
IgG
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Discover our top product TPMT Primary Antibody
Alternatives
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使用细节
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应用备注
IF 1:50-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
TPMT目标详情
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抗原
TPMT
(Thiopurine S-Methyltransferase (TPMT))
别名
TPMT (TPMT 产品 )
别名
MGC84277 antibody, AW106912 antibody, NHLRC1 antibody, thiopurine S-methyltransferase L homeolog antibody, thiopurine S-methyltransferase, tandem duplicate 2 antibody, thiopurine S-methyltransferase TpmT antibody, thiopurine S-methyltransferase antibody, Thiopurine S-methyltransferase antibody, thiopurine methyltransferase antibody, tpmt.L antibody, tpmt.2 antibody, tpmT antibody, MCA0794 antibody, Pnap_4948 antibody, Hhal_1383 antibody, TK90_1044 antibody, Slit_1144 antibody, Tint_0842 antibody, Fbal_3334 antibody, Celly_3188 antibody, Weevi_1737 antibody, Psefu_2696 antibody, Metme_3860 antibody, Tpmt antibody, TPMT antibody
背景
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
基因ID
7172
UniProt
P51580
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