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- 抗原 See all EFCAB4B 抗体
- EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EFCAB4B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human CRACR2A (NP_001138430.1).
- 亚型
- IgG
- Top Product
- Discover our top product EFCAB4B Primary Antibody
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anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 1-200) antibody
EFCAB4B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 1-395) antibodyEFCAB4B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 215-264) antibodyEFCAB4B 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 71-120) antibodyEFCAB4B 适用: 人, 大鼠, 马, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
- 别名
- CRACR2A (EFCAB4B 产品)
- 别名
- CRACR2A antibody, Gm1073 antibody, Gm462 antibody, calcium release activated channel regulator 2A antibody, CRACR2A antibody, Cracr2a antibody
- 背景
- Ca2+-binding protein that plays a key role in store-operated Ca2+entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
- 分子量
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Observed_MW: 45 kDa
Calculated_MW: 45 kDa/83 kDa
- 基因ID
- 84766
- UniProt
- Q9BSW2
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