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- 抗原 See all PMS2 抗体
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PMS2 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human PMS2 (NP_000526.2).
- 亚型
- IgG
- Top Product
- Discover our top product PMS2 Primary Antibody
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anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibody
PMS2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E9D11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibodyPMS2 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8E4G11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) antibodyPMS2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6G12E1 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) antibodyPMS2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 763-862) antibodyPMS2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 390-670) antibodyPMS2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) antibodyPMS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 763-862) antibodyPMS2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4A8 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (C-Term) antibodyPMS2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) antibodyPMS2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 349-29-5-2 unconjugated
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- 应用备注
- IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
- 别名
- PMS2 (PMS2 产品)
- 别名
- HNPCC4 antibody, PMS2CL antibody, PMSL2 antibody, AW555130 antibody, Pmsl2 antibody, PMS1 homolog 2, mismatch repair system component antibody, PMS1 homolog2, mismatch repair system component antibody, mismatch repair endonuclease PMS2 antibody, PMS2 antibody, Pms2 antibody, LOC463257 antibody, LOC107984056 antibody
- 背景
- The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC, also known as Lynch syndrome) and Turcot syndrome.
- 基因ID
- 5395
- UniProt
- P54278
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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