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TNFRSF1B 抗体
TNFRSF1B
适用: 人, 小鼠, 大鼠
IHC
宿主: 兔
Polyclonal
unconjugated
TNFRSF1B抗体详情
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抗原
See all TNFRSF1B 抗体
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
适用
All reactivities for TNFRSF1B 抗体
人, 小鼠, 大鼠
宿主
All hosts for TNFRSF1B 抗体
兔
克隆类型
All clonalities for TNFRSF1B 抗体
多克隆
标记
All conjugates for TNFRSF1B 抗体
This TNFRSF1B antibody is un-conjugated
应用范围
All applications for TNFRSF1B 抗体
Immunohistochemistry (IHC)
产品特性
Polyclonal Antibody
纯化方法
Affinity purification
免疫原
Recombinant fusion protein of human TNFRSF1B (NP_001057.1).
亚型
IgG
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Discover our top product TNFRSF1B Primary Antibody
Alternatives
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使用细节
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应用备注
IHC 1:50-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
TNFRSF1B目标详情
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抗原
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
别名
TNFRSF1B (TNFRSF1B 产品 )
别名
CD120b antibody, TBPII antibody, TNF-R-II antibody, TNF-R75 antibody, TNFBR antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, p75 antibody, p75TNFR antibody, TNF-RII/TNFRSF1B antibody, TNFR-II antibody, TNFRSF1B antibody, TNF-R2 antibody, TNF-alphaR2 antibody, TNFRII antibody, TNFalpha-R2 antibody, Tnfr-1 antibody, Tnfr2 antibody, rank antibody, zgc:163064 antibody, TNF receptor superfamily member 1B antibody, tumor necrosis factor receptor superfamily, member 1b antibody, tumor necrosis factor receptor superfamily, member 1B antibody, TNFRSF1B antibody, Tnfrsf1b antibody, tnfrsf1b antibody
背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
基因ID
7133
UniProt
P20333
途径
NF-kappaB Signaling , Apoptosis , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Ubiquitin Proteasome Pathway
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