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Aminoacylase 1 抗体

ACY1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7257008
发货至: 中国
  • 抗原 See all Aminoacylase 1 (ACY1) 抗体
    Aminoacylase 1 (ACY1)
    适用
    • 31
    • 13
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 21
    • 12
    • 2
    克隆类型
    • 23
    • 12
    多克隆
    标记
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aminoacylase 1 antibody is un-conjugated
    应用范围
    • 26
    • 14
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human ACY1 (NP_001185824.1).
    亚型
    IgG
    Top Product
    Discover our top product ACY1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Aminoacylase 1 (ACY1)
    别名
    ACY1 (ACY1 产品)
    别名
    si:zfos-226g1.1 antibody, zgc:55605 antibody, zgc:76955 antibody, acy1 antibody, acy1d antibody, acylase antibody, ACY1 antibody, ACY-1 antibody, ACY1D antibody, 1110014J22Rik antibody, Acy-1 antibody, Acy1a antibody, Acy1b antibody, aminoacylase 1 antibody, aminoacylase 1, gene 1 S homeolog antibody, aminoacylase 1, gene 1 antibody, ACY1 antibody, acy1 antibody, acy1.1.S antibody, acy1.1 antibody, Acy1 antibody
    背景
    This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
    基因ID
    95
    UniProt
    Q03154
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