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MBTPS1 抗体

MBTPS1 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256896
发货至: 中国
  • 抗原 See all MBTPS1 抗体
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    适用
    • 28
    • 12
    • 11
    宿主
    • 27
    • 1
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBTPS1 antibody is un-conjugated
    应用范围
    • 15
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human MBTPS1 (NP_003782.1).
    亚型
    IgG
  • 应用备注
    IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    别名
    MBTPS1 (MBTPS1 产品)
    别名
    PCSK8 antibody, S1P antibody, SKI-1 antibody, 0610038M03Rik antibody, AV003995 antibody, Ski1 antibody, mKIAA0091 antibody, S1p antibody, Ski-1 antibody, membrane bound transcription factor peptidase, site 1 antibody, membrane-bound transcription factor peptidase, site 1 antibody, MBTPS1 antibody, Mbtps1 antibody
    背景
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
    基因ID
    8720
    UniProt
    Q14703
    途径
    ER-Nucleus Signaling
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