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TDG 抗体

TDG 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256880
发货至: 中国
  • 抗原 See all TDG 抗体
    TDG (Thymine-DNA Glycosylase (TDG))
    适用
    • 47
    • 19
    • 11
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 37
    • 11
    克隆类型
    • 40
    • 9
    多克隆
    标记
    • 42
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TDG antibody is un-conjugated
    应用范围
    • 39
    • 12
    • 10
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human TDG (NP_003202.3).
    亚型
    IgG
    Top Product
    Discover our top product TDG Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TDG (Thymine-DNA Glycosylase (TDG))
    别名
    TDG (TDG 产品)
    别名
    5-MCDG antibody, wu:fb44b11 antibody, zgc:110622 antibody, MGC82456 antibody, MGC89441 antibody, E130317C12Rik antibody, JZA-3 antibody, Jza1 antibody, hTDG antibody, thymine DNA glycosylase antibody, thymine DNA glycosylase, tandem duplicate 1 antibody, putative g/t mismatch-specific thymine DNA glycosylase antibody, G/T mismatch-specific thymine DNA glycosylase antibody, thymine DNA glycosylase S homeolog antibody, thymine-DNA glycosylase antibody, TDG antibody, tdg.1 antibody, Smp_149220 antibody, Tsp_05734 antibody, tdg.S antibody, tdg antibody, Tdg antibody
    背景
    The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
    基因ID
    6996
    UniProt
    Q13569
    途径
    DNA Damage Repair, Chromatin Binding
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