COASY 抗体
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- 抗原 See all COASY 抗体
- COASY (CoA Synthase (COASY))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COASY antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human COASY (NP_079509.5).
- 亚型
- IgG
- Top Product
- Discover our top product COASY Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- COASY (CoA Synthase (COASY))
- 别名
- COASY (COASY 产品)
- 别名
- DPCK antibody, NBP antibody, PPAT antibody, UKR1 antibody, pOV-2 antibody, 1300003G02Rik antibody, Dpck antibody, Ppat antibody, Ukr1 antibody, COASY antibody, zgc:92337 antibody, PPAT/DPCK antibody, Coenzyme A synthase antibody, CoA synthase antibody, bifunctional coenzyme A synthase antibody, Bifunctional coenzyme A synthase antibody, COASY antibody, Coasy antibody, CpipJ_CPIJ008826 antibody, pco122135 antibody, coasy antibody
- 背景
- Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.
- 分子量
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Observed_MW: 62 kDa
Calculated_MW: 62 kDa/65 kDa
- 基因ID
- 80347
- UniProt
- Q13057
- 途径
- Ribonucleoside Biosynthetic Process
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