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CDC42 抗体
CDC42
适用: 人, 小鼠, 大鼠
IHC
宿主: 兔
Polyclonal
unconjugated
CDC42抗体详情
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抗原
See all CDC42 抗体
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
适用
All reactivities for CDC42 抗体
人, 小鼠, 大鼠
宿主
All hosts for CDC42 抗体
兔
克隆类型
All clonalities for CDC42 抗体
多克隆
标记
All conjugates for CDC42 抗体
This CDC42 antibody is un-conjugated
应用范围
All applications for CDC42 抗体
Immunohistochemistry (IHC)
产品特性
Polyclonal Antibody
纯化方法
Affinity purification
免疫原
Recombinant fusion protein of human CDC42 (NP_001782.1).
亚型
IgG
Top Product
Discover our top product CDC42 Primary Antibody
Alternatives
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anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 38-87) antibody
CDC42
适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 猴, 小鸡, 兔, 非洲爪蟾, 马, Avian, 豚鼠, Insect
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
IHC 1:50-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
CDC42目标详情
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抗原
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
别名
CDC42 (CDC42 产品 )
别名
CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
背景
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
基因ID
998
UniProt
P60953
途径
MAPK Pathway , Microtubule Dynamics , RTK signaling , WNT signaling , TCR Signaling , EGFR Signaling Pathway , Regulation of Actin Filament Polymerization , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Maintenance of Protein Location , Skeletal Muscle Fiber Development , Signaling Events mediated by VEGFR1 and VEGFR2 , EGFR Downregulation , VEGF Signaling
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