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ZNF828 抗体

ZNF828 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7255730
发货至: 中国
  • 抗原 See all ZNF828 抗体
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    适用
    • 43
    • 21
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 2
    克隆类型
    • 43
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNF828 antibody is un-conjugated
    应用范围
    • 36
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human CHAMP1 (NP_115812.1).
    亚型
    IgG
    Top Product
    Discover our top product ZNF828 Primary Antibody
  • 应用备注
    IF 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    别名
    CHAMP1 (ZNF828 产品)
    别名
    ZNF828 antibody, C13orf8 antibody, CAMP antibody, CHAMP antibody, AA675043 antibody, AI116001 antibody, D8Ertd457e antibody, D8Ertd569e antibody, Zfp828 antibody, Znf828 antibody, mKIAA1802 antibody, chromosome alignment maintaining phosphoprotein 1 antibody, CHAMP1 antibody, Champ1 antibody
    背景
    CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
    基因ID
    283489
    UniProt
    Q96JM3
    途径
    Maintenance of Protein Location
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