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LGMN 抗体

LGMN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7255373
发货至: 中国
  • 抗原 See all LGMN 抗体
    LGMN (Legumain (LGMN))
    适用
    • 51
    • 24
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 7
    克隆类型
    • 46
    • 6
    多克隆
    标记
    • 25
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGMN antibody is un-conjugated
    应用范围
    • 44
    • 22
    • 14
    • 8
    • 8
    • 7
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human LGMN (NP_001008530.1).
    亚型
    IgG
    Top Product
    Discover our top product LGMN Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LGMN (Legumain (LGMN))
    别名
    LGMN (LGMN 产品)
    背景
    This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.
    基因ID
    5641
    UniProt
    Q99538
    途径
    Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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