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HLA-F 抗体

HLAF 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7255293
发货至: 中国
  • 抗原 See all HLA-F (HLAF) 抗体
    HLA-F (HLAF) (HLA Class I alpha F (HLAF))
    适用
    • 17
    • 2
    • 2
    • 2
    • 1
    人, 大鼠
    宿主
    • 14
    • 3
    克隆类型
    • 13
    • 4
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    This HLA-F antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human HLA-F (NP_001091949.1).
    亚型
    IgG
    Top Product
    Discover our top product HLAF Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HLA-F (HLAF) (HLA Class I alpha F (HLAF))
    别名
    HLA-F (HLAF 产品)
    别名
    HLAF antibody, CDA12 antibody, HLA-5.4 antibody, HLA-CDA12 antibody, major histocompatibility complex, class I, F antibody, HLA-F antibody
    背景
    This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
    分子量

    Observed_MW: 50 kDa

    Calculated_MW: 28 kDa/39 kDa/50 kDa

    基因ID
    3134
    UniProt
    P30511
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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