Meprin B 抗体
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- 抗原 See all Meprin B (MEP1B) 抗体
- Meprin B (MEP1B) (Meprin A, beta (MEP1B))
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Meprin B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human MEP1B (NP_005916.2).
- 亚型
- IgG
- Top Product
- Discover our top product MEP1B Primary Antibody
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- 应用备注
- WB 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Meprin B (MEP1B) (Meprin A, beta (MEP1B))
- 别名
- MEP1B (MEP1B 产品)
- 别名
- MEP1B antibody, si:ch211-191a24.6 antibody, zgc:153272 antibody, Mep-1b antibody, meprin A subunit beta antibody, meprin A, beta antibody, meprin 1 beta antibody, MEP1B antibody, LOC100031050 antibody, mep1b antibody, LOC100545010 antibody, Mep1b antibody
- 背景
- Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
- 分子量
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Observed_MW: 105 kDa
Calculated_MW: 79 kDa
- 基因ID
- 4225
- UniProt
- Q16820
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