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- 抗原 See all EIF3A 抗体
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human EIF3A (NP_003741.1).
- 亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1-250) antibody
EIF3A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1288-1379) antibodyEIF3A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1-75) antibodyEIF3A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1-75) antibodyEIF3A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (C-Term) antibodyEIF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 550-600) antibodyEIF3A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (C-Term) antibodyEIF3A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1219-1247), (C-Term) antibodyEIF3A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32052 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (C-Term) antibodyEIF3A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 斑马鱼, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 172-202), (C-Term) antibodyEIF3A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
- 别名
- EIF3A (EIF3A 产品)
- 别名
- EIF3 antibody, EIF3S10 antibody, P167 antibody, TIF32 antibody, eIF3-p170 antibody, eIF3-theta antibody, p180 antibody, p185 antibody, EIF6 antibody, A830012B05Rik antibody, Csma antibody, Eif3 antibody, Eif3s10 antibody, mKIAA0139 antibody, ZH12 antibody, eif3s10 antibody, eIF3 p110 antibody, eIF3a antibody, eukaryotic translation initiation factor 3 subunit A antibody, eukaryotic translation initiation factor 3, subunit A antibody, eukaryotic translation initiation factor 3 subunit A S homeolog antibody, translation initiation factor eIF3a antibody, EIF3A antibody, Eif3a antibody, eif3a.S antibody, tif32 antibody
- 背景
- RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
- 分子量
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Observed_MW: 180 kDa
Calculated_MW: 162 kDa/166 kDa
- 基因ID
- 8661
- UniProt
- Q14152
- 途径
- Ribonucleoprotein Complex Subunit Organization
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