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MDM2 抗体
MDM2
适用: 人, 小鼠, 大鼠
IHC, IF
宿主: 兔
Polyclonal
unconjugated
MDM2抗体详情
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抗原
See all MDM2 抗体
MDM2
(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
适用
All reactivities for MDM2 抗体
人, 小鼠, 大鼠
宿主
All hosts for MDM2 抗体
兔
克隆类型
All clonalities for MDM2 抗体
多克隆
标记
All conjugates for MDM2 抗体
This MDM2 antibody is un-conjugated
应用范围
All applications for MDM2 抗体
Immunohistochemistry (IHC), Immunofluorescence (IF)
产品特性
Polyclonal Antibody
纯化方法
Affinity purification
免疫原
A synthetic peptide of human MDM2 (NP_002383.2).
亚型
IgG
Top Product
Discover our top product MDM2 Primary Antibody
Alternatives
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使用细节
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应用备注
IHC 1:50-1:200 IF 1:50-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
MDM2目标详情
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抗原
MDM2
(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
别名
MDM2 (MDM2 产品 )
别名
ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
背景
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
基因ID
4193
UniProt
Q00987
途径
p53 Pathway , PI3K-Akt Signaling , Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Autophagy , Ubiquitin Proteasome Pathway
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