VASP 抗体
Quick Overview for VASP 抗体 (ABIN7007086)
抗原
See all VASP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein of human VASP
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
-
别名
- VASP
-
背景
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
-
分子量
-
Observed_MW: 48 kDa
Calculated_MW: 39 kDa
-
基因ID
- 7408
-
UniProt
- P50552
-
途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
抗原
-