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Perforin 1 抗体

PRF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7254750
发货至: 中国
  • 抗原 See all Perforin 1 (PRF1) 抗体
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    适用
    • 81
    • 23
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 43
    • 4
    克隆类型
    • 56
    • 46
    多克隆
    标记
    • 57
    • 13
    • 12
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Perforin 1 antibody is un-conjugated
    应用范围
    • 47
    • 40
    • 34
    • 22
    • 16
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human Perforin (NP_001076585.1).
    亚型
    IgG
    Top Product
    Discover our top product PRF1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    别名
    Perforin (PRF1 产品)
    别名
    FLH2 antibody, HPLH2 antibody, P1 antibody, PFN1 antibody, PFP antibody, PRF1 antibody, Pfn antibody, Pfp antibody, Prf-1 antibody, Cyta antibody, RATCYTA antibody, LOC443187 antibody, perforin antibody, prf1 antibody, cytolysin antibody, perforin-1 antibody, perforin-1-like antibody, perforin 1 antibody, perforin 1 (pore forming protein) antibody, perforin antibody, perforin 1 L homeolog antibody, PRF1 antibody, Prf1 antibody, LOC443187 antibody, prf1 antibody, prf1.L antibody
    背景
    The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
    分子量

    Observed_MW: 70 kDa

    Calculated_MW: 61 kDa

    基因ID
    5551
    UniProt
    P14222
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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