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RECQL2 抗体

WRN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7254655
发货至: 中国
  • 抗原 See all RECQL2 (WRN) 抗体
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    适用
    • 38
    • 2
    • 1
    宿主
    • 31
    • 7
    克隆类型
    • 31
    • 7
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RECQL2 antibody is un-conjugated
    应用范围
    • 29
    • 17
    • 11
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human WRN
    亚型
    IgG
    Top Product
    Discover our top product WRN Primary Antibody
  • 应用备注
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.8 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    别名
    WRN (WRN 产品)
    背景
    This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
    UniProt
    Q14191
    途径
    DNA Damage Repair
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