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- 抗原 See all HLA-DMB 抗体
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DMB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human HLA-DMB
- 亚型
- IgG
- Top Product
- Discover our top product HLA-DMB Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibody
HLA-DMB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 40-100) antibodyHLA-DMB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B3 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 81-100), (Middle Region) antibodyHLA-DMB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 1-263) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (N-Term) antibodyHLA-DMB 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.38 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
- 别名
- HLA-DMB (HLA-DMB 产品)
- 别名
- RING7 antibody, D6S221E antibody, RT1.DMb antibody, RT1.Mb antibody, MHC-DMB antibody, major histocompatibility complex, class II, DM beta antibody, RT1 class II, locus DMb antibody, HLA-DMB antibody, RT1-DMb antibody, PATR-DMB antibody
- 背景
- HLA-DMB (Major Histocompatibility Complex, Class II, DM Beta) is a Protein Coding gene. Diseases associated with HLA-DMB include Red-Green Color Blindness and Red Color Blindness. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and CTLA4 Signaling. GO annotations related to this gene include MHC class II protein complex binding. An important paralog of this gene is ENSG00000248993.HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 29 kDa
- UniProt
- P28068
- 途径
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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