UNC45B 抗体
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- 抗原 See all UNC45B 抗体
- UNC45B (Unc-45 Homolog B (UNC45B))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UNC45B antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human UNC45B
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.9 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- UNC45B (Unc-45 Homolog B (UNC45B))
- 别名
- UNC45B (UNC45B 产品)
- 别名
- MGC80931 antibody, cmya4 antibody, AA445617 antibody, Cmya4 antibody, D230041A13Rik antibody, Unc45 antibody, CMYA4 antibody, SMUNC45 antibody, UNC45 antibody, Unc-45B antibody, cb393 antibody, unc45r antibody, wu:fa05a03 antibody, wu:fa10f03 antibody, wu:fb37f02 antibody, wu:fb96f06 antibody, wu:fc10f04 antibody, unc-45 myosin chaperone B S homeolog antibody, unc-45 myosin chaperone B antibody, unc45b.S antibody, unc45b antibody, UNC45B antibody, Unc45b antibody
- 背景
- This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 104/95 kDa
- UniProt
- Q8IWX7
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