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UNC45B 抗体

UNC45B 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7252228
发货至: 中国
  • 抗原 See all UNC45B 抗体
    UNC45B (Unc-45 Homolog B (UNC45B))
    适用
    • 27
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 25
    • 2
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC45B antibody is un-conjugated
    应用范围
    • 16
    • 14
    • 9
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human UNC45B
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.9 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    UNC45B (Unc-45 Homolog B (UNC45B))
    别名
    UNC45B (UNC45B 产品)
    背景
    This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 104/95 kDa

    UniProt
    Q8IWX7
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