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- 抗原 See all EDARADD 抗体
- EDARADD (EDAR-Associated Death Domain (EDARADD))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDARADD antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Full length fusion protein
- 亚型
- IgG
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anti-EDAR-Associated Death Domain (EDARADD) (AA 1-215) antibody
EDARADD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:35-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.9 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- EDARADD (EDAR-Associated Death Domain (EDARADD))
- 别名
- EDARADD (EDARADD 产品)
- 别名
- 1810032E07Rik antibody, 5830469M23Rik antibody, A630043P06 antibody, cr antibody, ECTD11A antibody, ECTD11B antibody, ED3 antibody, EDA3 antibody, EDAR (ectodysplasin-A receptor)-associated death domain antibody, EDAR associated death domain antibody, Edaradd antibody, EDARADD antibody
- 背景
- This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- UniProt
- Q8WWZ3
- 途径
- Ubiquitin Proteasome Pathway
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