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- 抗原 See all SPACA3 抗体
- SPACA3 (Sperm Acrosome Associated Protein 3 (SPACA3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPACA3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Full length fusion protein
- 亚型
- IgG
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anti-Sperm Acrosome Associated Protein 3 (SPACA3) (C-Term) antibody
SPACA3 适用: 人, 小鼠, 大鼠, 马, Pig, 兔, 绵羊, Cow, 犬, 山羊 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.5 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SPACA3 (Sperm Acrosome Associated Protein 3 (SPACA3))
- 别名
- SPACA3 (SPACA3 产品)
- 别名
- 1700025M08Rik antibody, ALLP17 antibody, CT54 antibody, LYC3 antibody, LYZL3 antibody, SLLP1 antibody, Lyc3 antibody, mSLLP1 antibody, SPRASA antibody, sperm acrosome associated 3 antibody, SPACA3 antibody, Spaca3 antibody
- 背景
- SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms, SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
- UniProt
- Q8IXA5
- 途径
- Glycosaminoglycan Metabolic Process
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