ATXN7L3 抗体
Quick Overview for ATXN7L3 抗体 (ABIN7252051)
抗原
See all ATXN7L3 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human ATXN7L3
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
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别名
- ATXN7L3
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背景
- Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 39 kDa
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UniProt
- Q14CW9
抗原
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