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PARP1 抗体 (Cleaved-Asp214)

PARP1 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7251022
发货至: 中国
  • 抗原 See all PARP1 抗体
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    抗原表位
    • 16
    • 15
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    • 10
    • 8
    • 8
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cleaved-Asp214
    适用
    • 216
    • 57
    • 45
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 209
    • 24
    • 1
    克隆类型
    • 202
    • 32
    多克隆
    标记
    • 132
    • 16
    • 15
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    • 12
    • 12
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    This PARP1 antibody is un-conjugated
    应用范围
    • 145
    • 118
    • 69
    • 32
    • 30
    • 25
    • 24
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    • 21
    • 17
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    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from the Internal region of human PARP-1
    亚型
    IgG
    Top Product
    Discover our top product PARP1 Primary Antibody
  • 应用备注
    WB 1:500-2000, IHC 1:50-300, IF 1:50-300
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    别名
    PARP1 (PARP1 产品)
    背景
    This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
    分子量

    Observed_MW: 24 kDa

    Calculated_MW: 113 kDa

    UniProt
    P09874
    途径
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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